Effects of Qidong Yixin Oral Liquid Combined with Trimetazidine Hydrochloride Tablets on Myocardial Injury Indexes,Immune Function and Oxidative Stress in Elderly Patients with Coronary Heart Disease and Angina Pectoris
Objective:To observe the effects of qidong yixin oral liquid combined with trimetazidine hydrochloride tablets on myocardial injury indexes,immune function and oxidative stress in elderly patients with coronary heart disease and angina pectoris.Methods:118 patients with angina pectoris of coronary heart disease admitted to our hospital from December 2020 to December 2022 were divided into control group(59 cases,treated with trimetazidine hydrochloride tablets)and study group(59 cases,treated with qidong yixin oral liquid combined with trimetazidine hydrochloride tablets)according to the random number table method.The cardiac function indexes,myocardial injury indexes,immune function indexes and oxidative stress indexes in two groups were compared.Results:The malondialdehyde(MDA),creatine kinase isoenzyme(CK-MB),cardiac troponin(cTnI),brain natriuretic peptide(BNP),CD8+were lower in study group 4 weeks after treatment,the left ventricular end-diastolic diameter(LVEDd)and left ventricular end-systolic diameter(LVESd)were smaller,and the superoxide dismutase(SOD),left ventricular ejection fraction(LVEF),CD3+,CD4+,CD4+/CD8+were higher(P＜0.05).Conclusion:Qidong Yixin oral liquid combined with trimetazidine hydrochloride tablets can effectively improve cardiac function,myocardial injury,immune function and oxidative stress indexes in elderly patients with coronary heart disease and angina pectoris.
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