Explore the Influencing Factors of PICC-Related Thrombosis in Elderly Cancer Patients Undergoing Chemotherapy at Home Based on Logistic and Decision Tree Models
Objective:To explore the influencing factors of peripherally inserted central catheter(PICC)-related thrombosis in elderly cancer patients undergoing chemotherapy at home based on Logistic and decision tree models.Methods:533 elderly cancer patients were divided into the occurrence group(n=53)and the non-occurrence group(n=480)according to whether PICC-related thrombosis occurred 1 month within catheter.The influencing factors was analyzed by multivariate Logistic and decision tree models.The predictive value was analyzed by receiver operating characteristic(ROC)curve.Results:High BMI,hypertension,previous history of thrombosis,daily activity time＜1 h,and failure to master PICC catheter maintenance knowledge were independent risk factors for PICC-related thrombosis,and the use of anticoagulant drugs was an independent protective factor(P＜0.05).The proportion of PICC-related thrombosis with previous history of thrombosis and daily activity time＜1 h were higher than those without previous history of thrombosis and daily activity time≥1 h.In the nodes without previous history of thrombosis,the proportion of PICC-related thrombosis in hypertension patients was higher than that in without hypertension patients.In hypertension patients,the proportion of PICC-related thrombosis in patients with BMI＞26.5 kg/m2 was higher than that in patients with 23.2 kg/m2＜BMI≤26.5 kg/m2 and BMI≤23.2 kg/m2.ROC curve analysis showed that,there was no significant difference in AUC between the two models.Conclusion:High BMI,previous history of thrombosis and daily activity time of less than 1 h are the influencing factors of PICC-related thrombosis in non-hospitalized elderly patients with tumor chemotherapy during home care obtained from Logistic regression and decision tree model statistics.Logistic regression and decision tree model can complement each other,and can replace the risk factors of PICC-related thrombosis,which is conducive to the accurate formulation of clinical prevention strategies.
ElderlyTumorChemotherapyAt homePeripherally inserted central catheterThrombosisDecision tree model
NETL
NSTL
万方数据
