Study on the Relationship between FFR,PLT/TBIL,MPV/PC and Major Adverse Cardiovascular Events after PCI in Patients with Coronary Heart Disease
Objective:To investigate the relationship between fractional flow reserve(FFR),platelet to total bilirubin ratio(PLT/TBIL),mean platelet volume to platelet count ratio(MPV/PC)and major adverse cardiovascular events(MACE)after percutaneous coronary intervention(PCI)in patients with coronary heart disease.Methods:230 patients with coronary heart disease who underwent PCI were retrospectively studied.According to the occurrence of MACE 1 year after operation,they were divided into MACE group(n=52)and non-MACE group(n=178).The influencing factors of MACE after PCI were analyzed by binary Logistic regression analysis,and the predictive efficacy of each index on MACE after PCI for coronary heart disease was analyzed by receiver operating characteristic curve(ROC).Results:Univariate analysis showed that there were differences in the number of diseased vessels,NYHA cardiac function classification,FFR,PLT/TBIL,MPV/PC between the two groups(P<0.05).Binary Logistic regression analysis showed that the number of diseased vessels(three-vessel lesion),NYHA cardiac function classification(Ⅳ),PLT/TBIL,MPV/PC were all influencing factors of MACE after PCI for coronary heart disease,while FFR was a protective factor(P<0.05).Conclusion:FFR,PLT/TBIL,MPV/PC are closely related to the occurrence of MACE after PCI in coronary heart disease,which can be used as an effective index to predict the occurrence of MACE after PCI in coronary heart disease.