Analysis of Influencing Factors and Prediction Model Establishment of Intestinal Fistula after Intestinal Resection in Ovarian Cancer Patients undergoing Cytoreductive Surgery
Objective:To investigate the influencing factors of intestinal fistula after intestinal resection of ovarian cancer cytore-ductive surgery.Methods:89 patients were divided into intestinal fistula group(n=16)and non-intestinal fistula group(n=73)according to whether postoperative intestinal fistula.The influencing factors was analyzed by univariate and multivariate Logistic regression models.The predictive value was analyzed by receiver operating characteristic(ROC)curve.Results:There were 16 cases intestinal fistula in 89 patients undergoing ovarian cancer cytoreductive surgery for intestinal resection,and the incidence of intestinal fistula was 17.98％.body mass index(BMI)≥24 kg/m2,elevated preoperative carbohydrate antigen 125(CA125),ascites volume,surgical complexity score,and intraoperative blood loss were independent risk factors for affecting intestinal fistula after intestinal resection in ovarian cancer cytoreduc-tive surgery patients(P＜0.05).And elevated preoperative albumin was a protective factor(P＜0.05).The results of ROC analysis showed that,the predictive efficacy of combined detection was better than that of single indicator.Conclusion:BMI,CA125,abdominal water volume,intraoperative blood loss,surgical complexity score and preoperative albumin were the influencing factors for postoperative intestinal fistula,and the combined detection had better predictive efficacy than single detection.
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