Diagnostic Value of Ultrasound Parameters of Endometrium-myometrium Junction Combined with Serum TGF-β1 and COX-2 in Adenomyosis
Objective:To investigate the diagnostic value of EMI ultrasound parameters combined with serum TGF-β1 and COX-2 for adenomyosis.Methods:Retrospective selection of 110 patients with adenomyosis from January 2021 to March 2023 as the observation group and 110 healthy women as the control group during the same period.All subjects underwent the same examinations and surgical procedures.Compare the diagnostic value of relevant indicators between two groups of subjects for adenomyosis.Results:The age of the observation group was significantly higher than that of the control group;73.64％of patients with adenomyosis have ab-normal EMI ultrasound findings;The EMI ultrasound parameters in the observation group were lower than those in the control group,with P values＜0.05.The serum levels of TGF-β1 and COX-2 in the observation group were higher than those in the control group,with P＜0.05.Increased average thickness,abnormal morphology,and elevated levels of TGF-β1 and COX-2 in EMI were risk factors for ade-nomyosis,while elevated EMI blood flow index was a protective factor for adenomyosis,with P＜0.05 for both.Among them,the average thickness and morphology of EMI;The combination of TGF-β1,COX-2 levels,blood flow index,and above indicators has good diag-nostic value for adenomyosis,with P values＜0.05.However,the AUC area of the combination of indicators for adenomyosis is larger than other indicators and can be used for the diagnosis of adenomyosis.Conclusion:EMI ultrasound parameters combined with serum TGF-β1 and COX-2 can be used for the diagnosis of adenomyosis.
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