FAR、SII及Caprini评分与老年肺癌患者术后下肢深静脉血栓形成的关系及风险预警模型构建
Relationship between FAR,SII and Caprini Score and Postoperative Deep Venous Thrombosis of Lower Extremity in Elderly Patients with Lung Cancer and Construction of a Risk Warning Model
李积安 1胡蕤 2马磊 3王程阳 3钟勇进3
作者信息
- 1. 西安市胸科医院血管介入科 陕西西安 710100
- 2. 陕西省人民医院重症医学科 陕西西安 710068
- 3. 西安市第九医院血管介入科 陕西西安 710054
- 折叠
摘要
目的:探讨纤维蛋白原/白蛋白比值(FAR)、系统免疫炎症指数(SII)及Caprini评分与老年肺癌患者术后下肢深静脉血栓形成(DVT)的关系,并构建列线图风险预警模型.方法:根据352例老年肺癌患者术后是否发生下肢DVT将其分为发生组(84例)和未发生组(268例).检测患者术后1 d的FAR、SII和Caprini评分.Logistic回归分析老年肺癌患者术后下肢DVT的影响因素,并构建列线图风险预警模型.结果:合并糖尿病、高脂血症、术前化疗、术后卧床时间延长、FAR、SII、Caprini评分均升高为老年肺癌患者术后下肢DVT的独立危险因素(P＜0.05).列线图风险预警模型的预测曲线与理想曲线贴合度良好,且H-L检验P＞0.05.结论:FAR、SII及Caprini评分均升高为老年肺癌患者术后下肢DVT的独立危险因素,构建的列线图风险预警模型对老年肺癌患者术后下肢DVT具有较高的预测价值.
Abstract
Objective:To investigate the relationship between fibrinogen/albumin ratio(FAR),systemic immune inflammation in-dex(SII)and Caprini score and postoperative deep venous thrombosis(DVT)of lower extremity in elderly patients with lung cancer,and to construct a nomogram risk warning model.Methods:According to whether the lower extremity DVT occurred in 352 elderly patients with lung cancer after operation,they were divided into occurrence group(84 cases)and non-occurrence group(268 cases).The FAR,SII and Caprini score of the patients at 1 day after operation were detected.The influencing factors of postoperative lower extremity DVT in elderly patients with lung cancer were analyzed by Logistic regression,and build a nomogram risk warning model.Results:Combined di-abetes mellitus,hyperlipidemia,preoperative chemotherapy,prolonged postoperative bed duration,and increased FAR,SII,and Caprini score were independent risk factors for postoperative lower extremity DVT in elderly patients with lung cancer(P＜0.05).The prediction curve of the nomogram risk early warning model was in good agreement with the ideal curve,and the H-L test P＞0.05.Conclusion:The increase of FAR,SII and Caprini score are independent risk factors for postoperative lower extremity DVT in elderly patients with lung cancer,and construction of nomogram risk warning model has a high predictive value for postoperative lower extremity DVT in elderly patients with lung cancer.
关键词
老年/肺癌/FAR/SII/Caprini评分/下肢深静脉血栓形成/列线图Key words
Elderly/Lung cancer/FAR/SII/Caprini score/Deep venous thrombosis of lower extremity/Nomogram引用本文复制引用
出版年
2024
NETL
NSTL
万方数据