Clinical Application of Natural Cycle IVF/M Combined with Oocyte Intracytoplasmic Sperm Injection in Male Infertility
Objective:To explore the clinical application of natural cycle Ⅳ F/M combined with oocyte ICSI in male infertility.Methods:2018.1-2023.8200 male infertility patients treated with assisted reproduction were divided into three groups according to the causes of less sperm,weak sperm and no sperm.Patients underwent either PESA or TESA and received 72 natural cycles of Ⅳ F/M.Comparing oocyte embryo development,pregnancy and delivery in the 3 groups.Results:There was no difference in the three groups of ovulation induction regimen,Gn use time,total Gn dosage,estradiol,LH,endometrial thickness,oocytes,immature oocytes,mature oocytes,cleavage rate,transplantable rate,and rate of high-quality embryos(P>0.05).The clinical pregnancy rate in anspermatozoa group was higher than that in weak sperm group and oligosperm group(P<0.05).Conclusion:Natural cycle Ⅳ F/M combined with ICSI is a simple and effective method to treat male infertility such as oligoasthenospermia and azoospermia.
Male infertilityIn vitro fertilizationImmature oocyteSperm injection