Value of Ultrasound Blood Flow Parameters of Middle Cerebral Artery in Evaluating the Degree of White Matter Lesions in Patients with Cerebral Small Vessel Disease
Objective:To analyze the value of ultrasound blood flow parameters of middle cerebral artery in evaluating the degree of white matter lesions(WMLs)in patients with cerebral small vessel disease(CSVD).Methods:A total of 98 patients with CSVD who were admitted to Yan'an University Affiliated Hospital between January 2021 and January 2024 were selected as the study group.Mean-while,60 healthy individuals were selected as the control group.The patients were divided into mild group(n=42),moderate group(n=36)and severe group(n=20)according to the severity of WMLs.Ultrasound examination was conducted to collect peak systolic blood flow velocity(Vs),peak diastolic blood flow velocity(Vd),mean blood flow velocity(Vm),pulsatility index(PI)and breath holding in-dex(BHI)of middle cerebral artery.The blood flow parameters of middle cerebral artery were compared between the study group and the control group as well as among patients with different severity of WMLs.Results:Vs,Vd,Vm and BHI of the study group were lower than those of the control group,and PI was higher than that of the control group(P＜0.05).There were significant differences in blood flow parameters of middle cerebral artery among patients with different severity of WMLs(P＜0.05).Compared with mild group,there were decreases in Vs,Vd,Vm and BHI,and increases in PI in moderate group and severe group(P＜0.05).Compared with moderate group,there were decreases in Vs,Vd,Vm and BHI,and increase in PI in severe group(P＜0.05).Conclusion:Ultrasound blood flow pa-rameters of middle cerebral artery are significantly correlated with the severity of WMLs in patients with CSVD,and can serve as non-in-vasive indicators for early evaluation of the severity of WMLs.
Cerebral small vessel diseaseWhite matter lesionsMean blood flow velocity of middle cerebral arteryPulsatility in-dexBreath holding indexEvaluation value
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