Analysis of the Relationship between Serum Macrophage Inflammatory Protein-1α,Neutrophil to Lymphocyte Count Ratio and the Risk of Pulmonary Infection after Renal Transplantation
Analysis of the Relationship between Serum Macrophage Inflammatory Protein-1α,Neutrophil to Lymphocyte Count Ratio and the Risk of Pulmonary Infection after Renal Transplantation
Objective:To analyze the relationship between serum macrophage inflammatory protein-1α(MIP-1α),peripheral blood neutrophil to lymphocyte count ratio(NLR)and the risk of pulmonary infection after renal transplantation.Methods:308 patients who underwent renal transplantation were selected,which were divided into uninfected group(n=253)and infected group(n=55)according to whether pulmonary infection occurred after operation.Serum MIP-1 α and peripheral blood NLR were compared in two groups.The risk factors affecting the occurrence of postoperative pulmonary infection were analyzed by multivariate logistic regression analysis.Results:The incidence of pulmonary infection in 308 renal transplant recipients was 17.86％at 1 year after operation.The serum MIP-1α and peripheral blood NLR in infected group were higher than those in uninfected group(P＜0.05).The independent risk factors for postoperative pulmonary infection in renal transplant recipients were increased MIP-1α,increased NLR,increased PCT,and smoking history(P＜0.05).Conclusion:The increase of serum MIP-1 α and peripheral blood NLR in renal transplant recipients will increase the risk of postoperative pulmonary infection.
关键词
肾移植/肺部感染/巨噬细胞炎性蛋白-1α/中性粒细胞与淋巴细胞计数比值
Key words
Renal transplantation/Pulmonary infection/Macrophage inflammatory protein-1α/Neutrophil to lymphocyte count ratio
维普
万方数据