目的:探讨布托啡诺、地佐辛联合加速术后康复外科(ERAS)、系统化镇痛管理在小儿麻醉中的应用效果。方法:采用随机数字表法将97例需行手术治疗的患儿分为对照组(接受布托啡诺、地佐辛治疗，n=48)和观察组(对照组基础上接受ERAS、系统化镇痛管理治疗，n=49)。对比两组疼痛视觉模拟评分(VAS)、Wong-Baker面部表情疼痛评分量表(FPS)评分、Ramsay镇静评分、平均动脉压(MAP)、心率(HR)、不良反应发生率变化情况。结果:观察组术后6 h Ramsay镇静评分高于对照组，FPS、VAS评分低于对照组(P＜0。05)。手术开始至手术结束后，观察组MAP、HR高于对照组(P＜0。05)。两组患儿不良反应发生率对比未见统计学差异(P＞0。05)。结论:布托啡诺、地佐辛联合ERAS、系统化镇痛管理应用于小儿麻醉，可有效镇静镇痛，维持血流动力学稳定，具有较好的安全性。
Analysis of the Application Effect of Butorphanol,Dezocine Combined with ERAS and Systematic Analgesia Management in Pediatric Anesthesia
Objective:To explore the application effect of butorphanol and dezocine combined with enhanced recovery after surgery(ERAS)and systematic analgesia management in pediatric anesthesia.Methods:97 children who needed surgical treatment were divided into control group(treated with butorphanol and dezocine,n=48)and observation group(treated with ERAS and systematic analgesia management on the basis of control group,n=49)by random number table method.The visual analogue scale(VAS),Wong-Baker facial expression pain scale(FPS)score,Ramsay sedation score,anesthesia awake time,orientation recovery time,mean arterial pressure(MAP),heart rate(HR)and incidence of adverse reactions were compared between two groups.Results:The Ramsay sedation score at 6 h after operation in observation group was higher than that in control group,and FPS and VAS scores were lower than those in control group(P＜0.05).From the start of operation until after operation,MAP and HR in observation group were higher than those in control group(P＜0.05).Comparison of the incidence of adverse reactions between two groups of children did not show any statistical difference(P＞0.05).Conclusion:The application of butorphanol,dezocine combined with ERAS and systematic analgesia management in pediatric anesthesia,which can effectively sedation and analgesia,maintain hemodynamic stability,and have good safety.
ButorphanolDezocineEnhanced recovery after surgerySystematic analgesia managementPediatric anesthesia
万方数据
维普
