Analysis of the Value of Adenosine Deaminase,Calcitoninogen,and Neutrophil-to-lymphocyte Ratio for the Diagnosis of Pneumonia Pathogens in Children and Their Relation to the Degree of Criticality
Objective:The value of adenosine deaminase(ADA),procalcitonin(PCT),neutrophil to lymphocyte ratio(NLR)in the diagnosis of pediatric pneumonia pathogens and its relationship with critical severity were analyzed.Methods:120 children with pneumonia admitted to our hospital from January 2023 to January 2024 were selected for the study.According to the types of infected pathogens,they were divided into bacterial pneumonia group(55 cases),viral pneumonia group(39 cases)and mycoplasma pneumonia group(26 cases),and relevant indicators were tested.Results:ADA,PCT and NLR expression were different among three groups(P<0.05);AUC of bacterial pneumonia,viral pneumonia and mycoplasma pneumonia were 0.812,0.803 and 0.789,respectively;serum ADA and PCT levels of children with severe pneumonia were higher than those of children without severe pneumonia(P<0.05);by Pearson correlation analysis,serum ADA and PCT levels in children with pneumonia were negatively correlated with PCIS score(P<0.05),positively associated with PSI score(P<0.05).Conclusion:ADA,PCT and NLR have a certain role in the diagnosis of pneumonia pathogens in children,among which ADA and PCT are closely related to the critical degree of children,which deserves clinical application.
Children pneumoniaAdenosine deaminaseProcalcitoninNeutrophil to lymphocyte ratio