首页|急性ST段抬高型心肌梗死患者血清FIB、TG/HDL-C比值、MPV/PC比值与院内新发心房颤动的关系研究

急性ST段抬高型心肌梗死患者血清FIB、TG/HDL-C比值、MPV/PC比值与院内新发心房颤动的关系研究

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目的:探讨急性ST段抬高型心肌梗死(ASTEMI)患者血清纤维蛋白原(FIB)、三酰甘油/高密度脂蛋白胆固醇(TG/HDL-C)比值、平均血小板体积/血小板计数(MPV/PC)比值与院内新发心房颤动(NOAF)的关系.方法:根据274例ASTEMI患者院内是否发生NOAF将其分为NOAF组(41例)和非NOAF组(233例),检测并对比两组FIB、TG/HDL-C比值、MPV/PC比值.采用多因素Logistic回归分析ASTEMI患者院内发生NOAF的影响因素.结果:NOAF组血清FIB、TG/HDL-C比值、MPV/PC比值高于非 NOAF 组(P<0.05).NOAF 组 Killip 分级≥ Ⅱ 级比例高于非 NOAF 组(P<0.05).Killip 分级≥ Ⅱ 级、血清 FIB、TG/HDL-C 比值、MPV/PC比值均升高是ASTEMI患者院内发生NOAF的独立危险因素.结论:ASTEMI患者血清FIB、TG/HDL-C比值、MPV/PC比值均升高,是患者院内发生NOAF的危险因素.
Study on the Relationship between Serum FIB,TG/HDL-C Ratio,MPV/PC Ratio and New-onset Atrial Fibrillation in Patients with Acute ST-Segment Elevation Myocardial Infarction
Objective:To investigate the relationship between serum fibrinogen(FIB),triglyceride/high-density lipoprotein choles-terol(TG/HDL-C)ratio,mean platelet volume/platelet count(MPV/PC)ratio and in-hospital new-onset atrial fibrillation(NOAF)in pa-tients with acute ST-segment elevation myocardial infarction(ASTEMI).Methods:274 ASTEMI patients were divided into NOAF group(41 cases)and Non NOAF group(233 cases)according to whether NOAF occurred in the hospital,FIB,TG/HDL-C ratio and MPV/PC ratio were detected and compared in two groups.The influencing factors of in-hospital NOAF in ASTEMI patients were analyzed by multivariate Logistic regression.Results:The serum FIB,TG/HDL-C ratio and MPV/PC ratio in NOAF group were higher than those in Non NOAF group(P<0.05).The proportion of Killip grade≥Ⅱ in NOAF group was higher than that in Non NOAF group(P<0.05).Kil-lip grade ≥ Ⅱ,elevated serum FIB,TG/HDL-C ratio,and MPV/PC ratio were independent risk factors for NOAF in ASTEMI patients.Conclusion:The serum FIB,TG/HDL-C ratio and MPV/PC ratio of ASTEMI patients are increased,which are the risk factors of NOAF in patients.

Acute ST-segment elevation myocardial infarctionFIBTG/HDL-C ratioMPV/PC ratioNew-onset atrial fibrillation

杨雪飞、王明、王云鹤、王倩、高贞青、李伟艺

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山东大学齐鲁医院德州医院心血管内科 山东德州 253000

山东大学齐鲁医院德州医院全科医学科 山东德州 253000

急性ST段抬高型心肌梗死 FIB TG/HDL-C比值 MPV/PC比值 新发心房颤动

2024

现代生物医学进展
黑龙江省森工总医院 哈尔滨医科大学附属第四医院

现代生物医学进展

CSTPCD
影响因子:0.755
ISSN:1673-6273
年,卷(期):2024.24(24)