Projections of Therapeutic Effects of Defibrillation in Patients with Wake-up Stroke Based on 3D-ASL Combined with mRS Score
Objective:Arterial spin labeling(Arterial Spin Labeling,ASL)is a non-invasive,quantitative brain perfusion MR imaging technique at the tissue level that can monitor blood flow changes in the area of acute cerebral infarction at an early stage.This study explores the diagnostic accuracy and sensitivity of 3D-ASL techniques in absolute brain blood flow(aCBF)and relative brain blood flow(rCBF)in wake stroke ischemia and analyzed the evaluation value of relevant parameter values for patient prognostic.Methods:se-lected 58 wake stroke patients(38 men and 20 women)from January 2019 to December 2020,head MRI TIWI,T2WI,DWI,MRA,3D-ASL,CBF and ADC,calculated rCBF and other parameters.After three months,patients were evaluated on improved Rankin(mRS)scale and analyzed collected data.Results:According to the mRS scale,there were 36 people,representing 62％and 22 people(mRS ≥ 3),representing 37.9％.aCBF has good diagnostic value in the evaluation of prognostic groups;higher rCBF values compared to prognostic groups;ROC curve indicates highest sensitivity and specificity when critical values aCBF=17.90,rCBF=40.9％.Conclusion:Different degrees of perfusion decreased in the waking stroke ischemic lesion area,and 3D-ASL was a reliable predictor on the prognosis of patients with waking stroke.
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