Advances in Quorum-sensing Bidirectional Interactions Between Phages and Bacteria
During the extensive co-evolutionary process,complex interactions have emerged between phages and bacterial hosts.Quorum sensing(QS)mechanisms play a prominent role in governing the interactions between phages and bacteria.This article begins by elucidating the exploitation of QS mechanisms by bacterial hosts,providing an overview of their consequential impacts on biofilm regulation,phage adsorption processes,and the modulation of the CRISPR-Cas system.Furthermore,the involvement of phages in QS mechanisms is expounded upon,encompassing a comprehensive survey of their role in phage lytic-lysogenic regulations and the suppression of QS mechanisms.Finally,this article presents a prospective investigation and explanation of phage QS mechanisms,aiming to provide a theoretical foundation for the application of QS mechanisms in the field of phage therapy and related areas.
Quorum sensingPhage-bacterial hostLysogen-lysisMicrobial interaction