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微生物群体感应在废水生物处理中的应用

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群体感应(quorum sensing,QS)作为依赖菌群密度调控基因表达的基因调控系统,被称为细胞间的交流语言.QS在许多 自然及废水处理工程系统中被发现,对环境修复及废水生物处理资源化起到重要的促进作用.总结细菌三种类型的典型信号分子(酰基高丝氨酸内酯类、寡肽类和呋喃酰硼酸二酯类)介导的QS机理,综述信号分子的添加或猝灭、基因的遗传操作、组学技术这三种研究QS系统功能的技术及并对比分析各种方法的优缺点,探讨QS在工业废水生物处理领域中活性污泥、生物膜及生物脱氮方面的应用.结合目前对QS的跨界通讯在废水处理方面的应用潜力和已知研究内容的局限性,对QS系统介导的细菌-植物、细菌-噬菌体、细菌-真菌跨界通讯机制等方面的研究进行展望,以期为利用QS调控策略强化废水处理效率提供新的思路.
Research Progress of Microbial Quorum Sensing in Waste water Biological Treatment
Quorum sensing(QS),known as the language of intercellular communication is a gene regulatory system that relies on colony density.It is found in many natural and wastewater treatment engineering systems and plays an important role in environmental remediation and wastewater biotreatment.At present,there is a lack of systematic summary of the research methods and related applications of QS regulating bacterial function.In this paper,the QS mechanism mediated by three types of typical signal molecules(N-Acyl homoserine 1 actones,autoinducing peptides and furanosyl borate diEnvironmental Science & Technologyer)of bacteria was summarized.The three techniques of adding or quenching signal molecules,genetic manipulation of genes,and omics techniques to study the function of the QS system were reviewed,and their advantages and disadvantages were compared and analyzed.The application of QS in activated sludge,biofilm and biological nitrogen removal in the field of industrial wastewater biological treatment was discussed.Finally,combined with the current application potential of QS cross-border communication in wastewater treatment and the limitations of known research contents,some studies on QS system-mediated bacterial-plant,bacterial-phage,bacterial-fungal cross-border communication mechanisms were discussed,in order to provide new ideas for using QS regulation strategies to enhance wastewater treatment efficiency in the future.

Wastewater biological treatmentBacteriaQuorum sensingSignal molecule

王倩、覃溢璇、孔强、李慧宇、宗可金、王颖慧、荣明慧

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山东师范大学地理与环境学院 济南 250358

山东师范大学东营研究院 东营 257343

废水生物处理 细菌 群体感应 信号分子

山东省自然科学基金

ZR2020YQ41

2024

中国生物工程杂志
中国科学院文献情报中心 中国生物技术发展中心 中国生物工程学会

中国生物工程杂志

CSTPCD北大核心
影响因子:0.589
ISSN:1671-8135
年,卷(期):2024.44(1)
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