铋基纳米材料在抗菌领域的研究进展
Research Progress on Bismuth-based Antibacterial Nanomaterials
张贵雪 1董晓艺 2潘洁 3李启艳3
作者信息
- 1. 大理大学药学院 大理 671000
- 2. 昆明理工大学材料科学与工程学院 昆明 650093
- 3. 云南省第一人民医院口腔医学中心 昆明 650032
- 折叠
摘要
铋(bismuth,Bi)作为一种低毒性重金属,已被用于合成各种具有独特结构和物理化学特性的纳米材料.合成的铋基纳米材料具有良好生物相容性、高X射线衰减系数、循环半衰期长、稳定性高、优异的光热转换效率和光催化能力等特点.由于这些特点,铋基纳米材料在组织工程、抗菌和癌症治疗等生物医学方面得到广泛应用.据报道,铋基纳米材料已被制成药物用于疾病治疗.与传统抗菌药物相比,铋基纳米材料在抗菌领域的应用可有效避免细菌耐药性的发生.综述了铋基纳米材料的特性、抗菌机制及其在抗菌领域的研究进展,最后提出了铋基纳米抗菌材料未来的研发方向.
Abstract
Bismuth(Bi),as a heavy metal of low toxicity,has been used to synthesize various nanomaterials with unique structure and physical and chemical properties.The synthesized bismuth-based nanomaterials have the characteristics of good biocompatibility,a favorably high X-ray attenuation coefficient,a long circulation half-life,high stability,excellent light-to-heat conversion efficiency and photocatalytic ability.Due to these properties,bismuth-based nanomaterials are widely used in biomedical fields such as tissue engineering,antibacterial materials and anti-cancer treatment.It is reported that bismuth-based nanomaterials have been made into drugs for the treatment of diseases.Compared with traditional antibacterial drugs,bismuth-based nanomaterials as antibacterial agents can effectively avoid the occurrence of bacterial drug resistance.The properties,antibacterial mechanism and progress in the antibacterial field of bismuth-based nanomaterials are reviewed.Furthermore,the future research direction of bismuth-based antibacterial nanomaterials is proposed.
关键词
铋基纳米材料/抗菌/生物医学/特性Key words
Bismuth-based nanomaterials/Antibacterial/Biomedicine/Properties引用本文复制引用
基金项目
云南省科技厅应用基础研究专项青年项目(202201AU070073)
云南省科技厅-昆明医科大学应用基础研究联合专项面上项目(202201AY070001-239)
云南省医学领军人才培养项目(L-2017019)
云南省第一人民医院院内博士项目(KHBS-2022-003)
出版年
2024
NETL
NSTL
万方数据