Research Progress on Extracellular Vesicles and Pulmonary Fibrosis
Pulmonary fibrosis is a disease characterized by irreversible structural and functional changes in the lung caused by excessive deposition of extracellular matrix proteins,resulting in fibrotic remodeling and alveolar destruction.As extracellular vesicles,exosomes can mediate intercellular communication by delivering functional nucleic acids and proteins produced by specific cell types.Recent studies have shown that exosomes play an important role in the diagnosis and treatment of pulmonary fibrosis and are considered to be a potential biological treatment method and drug delivery carrier.This review aims to summarize the current research on the role and therapeutic application of exosomes in pulmonary fibrosis,and to provide insights into the future development direction and prospects of exosome research,so as to provide new ideas for the treatment of exosomes in pulmonary fibrosis.
ExosomesPulmonary fibrosisExtracellular vesiclesDrug delivery vehicleDiagnosis and treatment