Recent Advances in MXene Hydrogels for Skin Wound Healing
Hydrogels have emerged as a promising treatment for skin wounds due to their ability to maintain a moist wound environment,mimic the extracellular matrix,encapsulate and deliver drugs and nanoparticles,and relieve pain.However,conventional hydrogels may not be effective for wounds with high levels of inflammation or microbial contamination,such as diabetic wounds and severe infections,due to their limited antibacterial and anti-inflammatory properties.Researchers have recently explored the potential of combining hydrogels with MXene nanomaterials to address these challenges.MXene is a two-dimensional layered nanomaterial that is widely employed in skin wound treatment due to its exceptional antibacterial,anti-inflammatory,antioxidant,drug delivery,and conductive properties.Combining MXene with hydrogel has effectively controlled wound infection,removed reactive oxygen species,and accelerated wound tissue regeneration.Furthermore,this combination can enhance the tissue adhesion and stability of MXene while reducing potential side effects associated with systemic administration of MXene.However,a comprehensive review of the MXene hydrogel as a wound dressing is still lacking.This review summarizes the latest research progress on MXene hydrogels for wound healing and discusses their challenges and prospects.
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