酵母合成虾青素的研究进展
Research Progress in the Synthesis of Astaxanthin by Yeast
舒钰洁 1王颖 1姚明东 1肖文海1
作者信息
- 1. 天津大学化工学院 天津 300072;天津大学合成生物学前沿科学中心和系统生物工程教育部重点实验室 天津 300072
- 折叠
摘要
虾青素是一种深红色酮类胡萝卜素,自然界中主要由藻类、细菌和浮游植物产生.作为天然色素和抗氧化物质在日化用品、医药行业、食品保健业、水产畜牧业有广泛应用.相较于天然提取和化学合成,利用异源微生物合成虾青素是一种绿色环保、经济高效的方法.概述虾青素生物合成路径,对微生物合成虾青素的研究现状和酵母合成虾青素的工程化策略进行总结,并对未来发展方向进行了展望.
Abstract
Astaxanthin is a crimson ketone carotene,which is mainly produced by algae,bacteria and phytoplankton.As a natural pigment and antioxidant,it is widely used in daily chemical products,pharmaceutical industry,food health industry,aquatic animal husbandry.Compared with natural extraction and chemical synthesis,the heterologous synthesis of astaxanthin by heterologous microorganisms is a green,economical and efficient method.The biosynthetic pathway of astaxanthin was introduced,the research status of microbial synthesis of astaxanthin and the engineering strategy of astaxanthin synthesis by yeast were summarized,and the future research prospects were discussed.
关键词
虾青素/类胡萝卜素/细胞工厂/合成生物学/代谢/酶/酵母Key words
Astaxanthin/Caroteneoid/Cell factory/Synthetic biology/Metabolism/Enzyme/Yeast引用本文复制引用
出版年
2024
NETL
NSTL
万方数据