Research and Application of Electrostatic Spray Poly(Lactic-co-glycolic Acid)Drug-loaded Microspheres in Medicine
Electrostatically sprayed polylactic acid-glycolic acid(PLGA)copolymer drug-loaded microspheres have promising medical applications due to their controllable particle size and morphology,high drug encapsulation rate,and ability to protect drug activity.The size and shape of microspheres have a significant impact on drug loading and absorption in vivo.By adjusting relevant parameters during electrostatic spraying,drug-loaded microspheres with specific characteristics can be produced.This article provides a comprehensive overview of electrostatic spraying,focusing on how various parameters impact the particle size and morphology of PLGA microspheres.It also delves into the utilization of drug-loaded microspheres in biomedicine and highlights the key challenges in this field.The findings presented heve are intended to serve as a valuable reference for ongoing research.
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维普
