Advances in the Biosynthesis and Metabolic Regulation of Tylosin
Tylosin,a 16-membered macrolide antibiotic produced by Streptomyces fradiae,is used in clinical practice primarily to treat bacterial infections caused by Gram-positive bacteria.It is widely used in animal husbandry and has high economic value and academic research value.The structural features and mechanism of tylosin are presented.The research progress in the biosynthesis regulation mechanism,the breeding of high-yield strains of S.fradiae and tylosin heterologous biosynthesis strategy are summarized,which will provide a useful reference for in-depth understanding of tylosin biosynthesis and metabolic regulation.
万方数据
维普
