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基于肠道菌群的植物挥发油药理作用机制研究进展

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人体肠道微生物群与人类疾病的发生发展密切相关,通过调控肠道菌群的结构与功能用于治疗疾病,已经成为临床治疗的重要手段.植物挥发油由于其对肠道菌群的多方面调节和毒副作用小等优势,已经成为当前研究的热点.以植物挥发油对肠道菌群的作用以及肠道微生物群与各类型疾病的关联为切入点,综述了近年来国内外植物挥发油调控肠道菌群发挥药理作用的内在机制研究,旨在为挥发油药理作用研究提供新思路.
Pharmacological Mechanism of Plant Essential Oils Based on Intestinal Flora:A Review
The human intestinal microbiota is closely related to the onset and development of human diseases,and it has become an important clinical treatment tool to regulate the structure and function of the intestinal flora for the treatment of diseases.Plant essential oil have become a hotspot of current research due to their advantages of multifaceted regulation of intestinal flora and low toxic side effects.Taking the role of plant volatile oils on intestinal flora and the association between intestinal microbiota and various types of diseases as a starting point,this paper reviews the research on the intrinsic mechanism of plant volatile oils regulating intestinal flora to exert pharmacological effects at home and abroad in recent years to provide a new way of thinking for the research on the pharmacological effects of volatile oils.

Plant essential oilIntestinal floraShort-chain fatty acidMechanism

邹宛聪、张海燕

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江西中医药大学 现代中药制剂教育部重点实验室 南昌 330004

植物挥发油 肠道菌群 短链脂肪酸 作用机制

2024

中国生物工程杂志
中国科学院文献情报中心 中国生物技术发展中心 中国生物工程学会

中国生物工程杂志

CSTPCD北大核心
影响因子:0.589
ISSN:1671-8135
年,卷(期):2024.44(12)