DNA甲基化与肠道微生物研究进展
Advances in DNA Methylation and Gut Microbes
龚静1
作者信息
- 1. 四川开放大学 农林卫生学院,四川成都 610073
- 折叠
摘要
肠道内的微生物群在维持肠道健康方面起着至关重要的作用.微生物表观遗传修饰包括DNA甲基化、组蛋白修饰、染色质重塑等.本文综述了环境因素对肠道微生物群、表观遗传修饰及其在肠道微生物和相关癌症发病过程中DNA甲基化领域的研究成果,对利用肠道微生物治疗相关癌症有一定的参考价值.
Abstract
The gut microbiota plays a crucial role in maintaining gut health.Microbial epigenetic modifications include DNA methylation,histone modification,chromatin remodeling etc.This article reviews the research progress in the field of environmental factors affecting gut microbiota,epigenetic modifications,and DNA methylation in gut microbiota and related cancer pathogenesis,which has certain reference value for the use of intestinal microbiota in the treatment of diseases
关键词
DNA甲基化/肠道微生物/肠道疾病/基因组学Key words
DNA methylation/intestinal microorganism/intestinal diseases/genomics引用本文复制引用
出版年
2024
NETL
NSTL
万方数据