Pathogen Spectrum and Drug Resistance of Bacterial Pneumonia in Children
Objective:To investigate the pathogenic spectrum and drug resistance of bacterial pneumonia in children in an area,and to provide a reference for the treatment of bacterial pneumonia in children in this area.Methods:The lower respiratory tract samples of children with bacterial pneumonia from January 2022 to December 2022 in a Grade 3A hospital in a region are collected for bacterial culture and drug sensitivity test.The difference of pathogenic bacteria detection in children of different sexes is analyzed.Results:A total of 481 strains of pathogenic bacteria are detected,259 strains of Gram negative bacteria,accounting for 53.8%;222 strains of Gram positive bacteria,accounting for 46.2%.The top four bacteria commonly infected are Moraxella catarrhalis,Staphylococcus aureus,Streptococcus pneumoniae and Haemophilus influenzae.The detection of Moraxella catarrhalis is the first in male children,and Staphylococcus aureus is the first in female children.There is no difference in the detection of major pathogens between different sexes(p＞0.05).Methicillin-resistant staphylococcus aureus(MRSA)accounted for 28.8%of Staphylococcus aureus,and the resistance rate to penicillin is as high as 82.6%.Streptococcus pneumoniae is 100%resistant to tetracycline,clindamycin and erythromycin,and no vancomycin and linezolid resistant strains are detected.The positive rates of β-lactamase in Moraxella catarrhalis and Haemophilus influenzae are 88.3%and 74.4%,respectively.The resistant rate of Moraxella catarrhalis to clindamycin is 92.0%,and the resistant rate of Haemophilus influenzae to ampicillin is 79.5%.Conclusion:The common pathogens of children's bacterial pneumonia infection in this area are Moraxella catarrhalis,Staphylococcus aureus,Streptococcus pneumoniae and Haemophilus influenzae,and the drug resistance rate of different pathogens to the same antibiotic varies greatly.This study provides a reference for the treatment of children's bacterial pneumonia in this area.
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