乌苏烷型五环三萜类化合物抗肿瘤研究进展
Research Progress in the Anti-Tumor Research of Ursane Pentacyclic Triterpenoids
陈子明 1吴天惠 1刘欣 1王兆博 1郭伟强 1刘恒蔚1
作者信息
- 1. 苏州科技大学 化学与生命科学学院,江苏苏州 215009
- 折叠
摘要
乌苏烷型五环三萜类化合物在植物中广泛存在,来源丰富,甘草、枇杷叶、苹果等含量较高.药理学研究表明此类化合物具有抗肿瘤、抗氧化、抗炎等生物活性,具有较大的医用价值和开发潜力.因此,本文针对近年来国内外有关乌苏烷型五环三萜类化合物抗肿瘤活性和作用机制的文献报道进行梳理,以期对此类化合物的进一步研究和抗肿瘤应用开发提供参考.
Abstract
Ursane pentacyclic triterpenoids are widely present in the natural plant kingdom and have abundant sources.They have a high content in plants such as licorice,loquat leaves,apples,etc.Pharmacological studies have shown that such compounds have biological activities such as anti-tumor,antioxidant,anti-inflammatory,and have lower toxic side effects,which has great medical value and development potential.This article reviews the literature reports on the anti-tumor activity and mechanism of action of ursane pentacyclic triterpenoids both domestically and internationally in recent years,in order to provide reference for further research and development of anti-tumor applications of these compounds.
关键词
乌苏烷型五环三萜/抗肿瘤/作用机制Key words
ursane pentacyclic triterpenoids/anti-tumor/mechanism of action引用本文复制引用
基金项目
国家自然科学基金(81502958)
江苏省研究生创新创业计划(KYCS22_3295)
出版年
2024
NETL
NSTL
万方数据