Transcription factors are a class of promising therapeutic targets,a major reason being that transcriptional dysregulation plays an important role in a variety of diseases.Due to the particularity of the structure of transcription factors,there are certain difficulties and challenges in drug development.However,as the theory that some transcription factors are undruggable has been broken in recent years,research on transcription factor drugs has set off an upsurge.This article summarizes the functions of transcription factors in tumor cells,diseases during development,immune diseases,etc.,and explores the drug targets of the three listed transcription factors.
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