Serum amyloid A(SAA)is an acute inflammatory response protein and can be used as one of the biomarkers of inflammation and tumor.In recent years,SAA has been widely used in the diagnosis and prevention of infectious diseases,but there is little literature to systematically review SAA detection methods and clinical applications.Therefore,this article summarizes the main detection methods and clinical applications of SAA,in order to provide reference for relevant researchers to further study SAA.