DNA-organic hybrid amphiphiles can self-assemble into various forms in aqueous solution,and adjusting their self-assembly form and size usually requires changing the internal structure of the molecule,or changing the assembly conditions and methods.Therefore,obtaining aggregates with a single morphological or dimensional variable is a huge challenge.In recent years,some scholars have proposed a new frame-guided assembly strategy,which guides the amphiphiles to aggregate along hydrophobic groups anchored to the frame,and finally forms a certain shape and uniform size according to the pre-designed frame.This strategy breaks through the limitations of traditional assembly methods,makes it possible to prepare aggregates with programmable geometry and size,provides a new idea and method for constructing nanostructures,and has potential application prospects in nanoscience and biomedicine.
NETL
NSTL
万方数据
