Astaxanthin has extremely strong antioxidant and anti-inflammatory effects,and has broad application prospects in fields such as food,medicine,feed,and cosmetics.In recent years,Phaffia rhodozyma has become the most promising microorganism for the biological production of astaxanthin,but the extraction of astaxanthin from Phaffia rhodozyma has always constrained its production.Based on this,this article provides an overview of the research progress on the wall breaking and astaxanthin extraction of Phaffia rhodozyma,in order to provide new ideas for the development of Phaffia rhodozyma yeast wall-breaking and astaxanthin extraction technology.