Application of Compound Preparations Containing B Vitamins in Facial Rejuvenation
Objective:To explore the efficacy and safety of preparing compound topical preparations with B vitamins in facial rejuvenation.Methods:A single-blind,self-controlled before and after trial is conducted in human subjects.33 subjects are selected to use the product continuously for 28 days,and their faces are evaluated for dermatology at baseline(0 d),day 14(14 d)and day 28(28 d),respectively.At the end of day 28,subjects should complete a self-assessment questionnaire and a safety assessment questionnaire.Results:After using the product on the day 14 and day 28,the moisture,elasticity,transdermal water loss and roughness parameters of the facial corneum are improved in 33 subjects.After using the product on day 28,the facial oil content is improved.The results of product safety evaluation show that 0 of 33 cases have skin adverse reactions.Conclusion:The compound preparation containing B vitamins can improve various skin aging phenomena and is a safe and effective external preparation for facial rejuvenation.
NETL
NSTL
万方数据
维普
