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岩藻多糖在代谢性疾病中的研究进展

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代谢性疾病是体内多种营养物质代谢异常所引发的疾病,包括高脂血症、糖尿病、动脉粥样硬化、代谢综合征以及高尿酸血症等多种疾病.代谢性疾病发病率高,并发症致死率高,是全球最受关注的公共卫生问题之一.岩藻多糖是一种从藻类生物中提取的富含岩藻糖的硫酸化多糖,多项临床前研究和临床试验已报道了岩藻多糖具有治疗糖尿病、降血脂、治疗高血压和改善肥胖的作用.本文概述了岩藻多糖在代谢性疾病中的研究进展,以及其在治疗代谢性疾病方面的作用机制,旨在为相关研究人员提供参考.
Research Progress of Fucoidan in Metabolic Diseases
Metabolic diseases are diseases caused by abnormal metabolism of various nutrients in the body,including hyperlipidemia,diabetes,atherosclerosis,metabolic syndrome,hyperuricemia and other diseases.Metabolic diseases have a high incidence rate and high mortality rate from complications,making them the most concerning public health issue in the world.Fucoidan is a sulfated polysaccharide rich in fucose extracted from algae organisms,and a number of preclinical studies and clinical trials have reported that fucoidan has the effect of treating diabetes,lowering blood lipids,treating hypertension and improving obesity.This article summarizes the research progress of fucoidan in metabolic diseases and its mechanism of action in the treatment of metabolic diseases,aiming to provide reference for relevant researchers.

fucoidanmetabolic diseasesdyslipidemiadiabetesobesity

李麦宁

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南京中医药大学,江苏 南京 210023

岩藻多糖 代谢性疾病 血脂异常 糖尿病 肥胖

2024

生物化工

生物化工

ISSN:
年,卷(期):2024.10(5)