GPRC5A在肿瘤细胞中表达的研究进展
Research Progress on the Expression of GPRC5A in Tumor Cells
李冯吉娜 1谭昌文 2钟迅 2付海晓 1徐龙宽1
作者信息
- 1. 桂林医学院附属医院,广西 桂林 541000
- 2. 桂林医学院,广西 桂林 541199
- 折叠
摘要
G蛋白偶联受体C家族 5A(GPRC5A)属于G蛋白偶联受体家族,在不同癌症中表达特点不同,还与恶性肿瘤的发生、发展、增殖和转移密切相关.本文重点综述了GPRC5A的特征及其与各类癌症(结直肠癌、肺癌、肝癌、胃癌、胰腺癌、乳腺癌、食管鳞癌及胆道系统恶性肿瘤)的关系,为后续研究该蛋白提供参考.
Abstract
G protein-coupled receptor C family 5A(GPRC5A)belongs to the G protein-coupled receptor family,which has different expression characteristics in different cancers,and is closely related to the occurrence,development,proliferation and metastasis of malignant tumors.This article focuses on the characteristics of GPRC5A and its relationship with various cancers(colorectal cancer,lung cancer,liver cancer,gastric cancer,pancreatic cancer,breast cancer,esophageal squamous cell carcinoma and biliary system malignancy),so as to provide a reference for subsequent research on this protein.
关键词
GPRC5A/G蛋白偶联受体家族/肿瘤细胞/临床意义Key words
GPRC5A/G protein-coupled receptor family/tumor cells/clinical significance引用本文复制引用
出版年
2024