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NDRG2: a Myc-repressed gene involved in cancer and cell stress

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As a master switch for cell proliferation and differentiation,Myc exerts its biological functions mainly through transcriptional regulation of its target genes,which are involved in cells' interaction and communication with their external environment.The N-Myc downstream-regulated gene (NDRG) family is composed ofNDRG1,NDRG2,NDRG3 and NDRG4,which are important in cell proliferation and differentiation.This review summarizes the recent studies on the structure,tissue distribution and functions of NDRG2 that try to show its significance in studying cancer and its therapeutic potential.

N-Myc downstream-regulated genetumor suppressorcell stress

Libo Yao、Jian Zhang、Xuewu Liu

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The Institute of Molecular Biology and the State Key Laboratory of Cancer Biology,Fourth Military Medical University,Xi'an 710032,China

教育部长江学者和创新团队发展计划国家自然科学基金国家自然科学基金国家自然科学基金国家自然科学基金国家自然科学基金国家自然科学基金

PCSIRT0459302280123037031530570676306704523070041606G092

2008

生物化学与生物物理学报(英文版)
中国科学院上海生物化学研究所

生物化学与生物物理学报(英文版)

CSTPCDCSCDSCI
影响因子：0.772
ISSN：1672-9145
年,卷(期)：2008.40(7)
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