Abstract
Biological control of pests and pathogens has attracted much attention due to its green,safe and effective char-acteristics.However,it faces the dilemma of insignificant effects in large-scale applications.Therefore,an in-depth exploration of the metabolic potential of biocontrol fungi based on big omics data is crucial for a comprehensive and systematic understanding of the specific modes of action operated by various biocontrol fungi.This article analyzes the preferences for extracellular carbon and nitrogen source degradation,secondary metabolites(nonribosomal peptides,polyketide synthases)and their product characteristics and the conversion relationship between extra-cellular primary metabolism and intracellular secondary metabolism for eight different filamentous fungi with characteristics appropriate for the biological control of bacterial pathogens and phytopathogenic nematodes.Further clarification is provided that Paecilomyces lilacinus,encoding a large number of hydrolase enzymes capable of degrading pathogen protection barrier,can be directly applied in the field as a predatory biocontrol fungus,whereas Trichoderma,as an antibiosis-active biocontrol control fungus,can form dominant strains on preferred substrates and produce a large number of secondary metabolites to achieve antibacterial effects.By clarifying the levels of biological control achievable by different biocontrol fungi,we provide a theoretical foundation for their application to cropping habitats.
基金项目
the grants from Key Research and Development Program of Shandong Province(2021CXGC010803)
国家重点研发计划(2023YFC3403601)
国家科技期刊平台
NSTL
万方数据