Advance in hypocrellin production by fermentation of Shiraia bambusicola
Hypocrellins,natural photosensitizers,are the bioactive ingredients of Shiraia bambusicola,a traditional Chinese medicinal fungus.Due to the limitation of the wild resources,hypocrellin production by fermentation of S.bambusicola has aroused widely interests.Hence,we reviewed the hypocrellin production in the solid and liquid cultures of anamorphic S.bambusicola.The cultural conditions including temperature,pH,carbon source,and nitrogen source were discussed.Some eliciting strategies for enhancing hypocrellin production and the breeding method for better germ resource were also concluded.This review could help explore biosynthesis of hypocrellin on industrial scale.