RNA interference (RNAi) is a phenomenon of post-transcriptional gene silencing triggered by highly conserved exogenous or endogenous double-strand RNA (dsRNA) during the evolution. RNAi, as an efficient and specific gene blocking technology, is widely applied to gene functional studies and the areas of treating infectious diseases and malignant tumors. RNAi has become one of the hotspots in the 21st century. This paper reviewed the several aspects of RNAi, including the history of discovering it, mechanism, characteristics, and the application prospects in fungal gene functional analysis, which may provide the theoretical basis for related researches.
国家科技期刊平台
NSTL
维普
万方数据
