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植物次生代谢的区室化研究进展

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植物次生代谢存在多层次的区室化现象,区室化对于植物的生长发育和环境胁迫响应具有重要意义.本文综述了植物次生代谢在分子水平、亚细胞水平、细胞水平和组织器官水平的区室化研究进展.次生代谢的区室化需要中间产物在不同区室间进行转运,因此转运蛋白是植物次生代谢产物区室化合成体系的重要组成部分.次生代谢区室化及其相关转运蛋白研究,丰富了植物次生代谢的理论基础,并且为天然产物合成生物学提供了新的靶点和研究策略.
Research Progress in the Compartmentalization of Plant Specialized Metabolism
Plant specialized metabolism(PSM)can be compartmentalized at multiple levels,which plays important roles in plant growth and development,as well as responses to environmental stress.Here we reviewed the recent advance in the compartmentalization of PSM at the molecular,subcellular,cellular and organ levels.Due to the compartmentation of PSM,the intermediates of biosynthesis pathway have to shuttle between different compartments.Therefore,the transporters are an important part of the compartmentalized biosynthesis system of specialized metabolites.The studies of the compartmentalization of PSM and its related transporters not only expand our knowledge about PSM,but also provide new targets and research strategies for the synthetic biology of natural products.

specialized metabolismcompartmentalizationtransporter

关智晶、孙超

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天津中医药大学,天津 301617

中国医学科学院药用植物研究所,北京 100193

次生代谢 区室化 转运蛋白

国家自然科学基金项目中国医学科学院医学与健康科技创新工程

820739612021-I2M-1-032

2024

生物技术通报
中国农业科学院农业信息研究所

生物技术通报

CSTPCD北大核心
影响因子:0.505
ISSN:1002-5464
年,卷(期):2024.40(1)
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