Research Progress in Three Major Mycotoxins and Their Toxin-degrading Enzymes
Feed during production and storage is often contaminated with mycotoxins,mainly including aflatoxin,zearalenone,vomitoxin,fumonisin B1,ochratoxin A and T-2 toxins.Mycotoxins cause serious physical injury or even death to livestock and poultry,and the coexistence of mycotoxins will lead to greater economic losses.The degradation of mycotoxins mainly includes chemical degradation,physical degradation and biological enzymatic hydrolysis.Biological enzymatic hydrolysisis more environmentally friendly and efficient than the other two methods,thus it has attracted much attention.In this paper,we analyzed the harmful mechanisms,degradation pathways and related mycotoxin-degrading enzymes of aflatoxin,zearalenone and vomitoxin with strong toxicity and wide pollution in detail.We revealed the interaction between toxin small molecules and mycotoxin-degrading enzymes in degradation reactions by molecular docking and other means,and screened the key amino acids in the degradation process.Although enzymatic hydrolysis possesses advantages in removing mycotoxins,its current application is still limited due to high cost and other reasons,and further research and development are urgently needed.Therefore,optimizing the process and conditions of enzymatic hydrolysis to achieve efficient and cost-effective removal of mycotoxins will be the focus of future research.This study provides an important reference to guide the design and optimization of mycotoxin-degrading enzymes.
万方数据
维普
