The Application Progress of Serum-free Suspension Culture Technology of MDCK Cells in Influenza Vaccine Study and Production
Influenza is a common respiratory disease caused by influenza viruses.MDCK(Madin-Darby Canine Kidney)cells have the characteristics of easy culture and high production,which can support the replication and proliferation of influenza viruses,and are widely used in the research and production of influenza viruses.With the deepening of research on influenza virus,and in order to further optimize the ability of MDCK cells to be used for influenza virus research and industrial application,researchers began to develop the domestication technology of MDCK cells.Through long-term cultivation and selection,the domesticated MDCK cells strain can better adapt to the growth environment of influenza virus,and improve the production and infectivity of influenza virus.In conclusion,the domestication technology of MDCK cells plays an important role in influenza virus research and industrial application,which may improve the production and infectivity of influenza viruses and provide better tools for influenza vaccine production and anti influenza drug development.Concurrently we have to also pay attention to the safety of MDCK cells and take appropriate measures to ensure the safety and reliability of its application.
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