微藻盐胁迫响应分子机制研究进展
Research Progress in the Molecular Mechanisms of Microalgae Responding to Salt Stress
沈天虹 1齐孝博 1赵瑞丰 1马欣荣1
作者信息
- 1. 天津科技大学省部共建食品营养与安全国家重点实验室,天津 300457;天津科技大学生物工程学院,天津 300457
- 折叠
摘要
微藻是地球上光合微生物的原始种类之一,由于其生长周期较短、生长速率较快和生产高附加值产物的潜力而被广泛开发利用.然而,在微藻放大生产的过程中极易受到高盐等非生物胁迫的不利影响,极大地限制了微藻的生产力.因此,了解微藻盐胁迫响应的分子机制将有助于耐盐藻株的快速建立.本文总结了真核微藻和原核蓝藻响应盐胁迫的各种参与蛋白及其具体作用机制,包括转运蛋白维持离子稳态、积累渗透调节物质、抗氧化防御机制、信号蛋白和脂质积累等;同时综述了已被开发利用的天然耐盐藻包括杜氏盐藻(Dunaliella salina)、盐生隐杆藻(Aphanothece halophytica)、皮克绿球藻(Picochlorum sp.)和海洋绿藻(Chlamydomonas W80)等微藻及其耐盐基因的研究进展;最后讨论了典型盐响应基因在优良藻种选育中的价值与应用前景.
Abstract
Microalgae,as one of the ancestors of photosynthetic microorganisms on earth,are widely exploited for its short growth cycle,fast growth rate and potential to produce high value-added products.However,their scale-up cultivations have been substantially hindered by those adverse effects resulting from various abiotic stresses including high salinity during industrial production processes.Therefore,it is extremely essential to understand the molecular mechanism of salt stress responses in microalgae,which may contribute to the build-up of genetically engineered microalgae or even higher plants.In this mini review,we summarized various proteins involved in the response of eukaryotic microalgae and prokaryotic cyanobacteria to salt stress and their specific mechanisms including transporters maintaining ion homeostasis,accumulating osmotic regulators,antioxidant defense mechanisms,signal proteins and lipid remodeling.Meanwhile,we outlined the recent research progress of halotolerant microalgae including Dunaliella salina,Aphanothece halophytica,Picochlorum sp.and Chlamydomonas W80,and their salt-tolerant genes that are mostly under active investigations.Finally,we briefly discussed the value and application prospect of typical important salt-responsive genes in the breeding of algal species.
关键词
真核微藻/原核蓝藻/盐胁迫/耐盐藻/盐胁迫响应分子机制Key words
eukaryotic microalgae/prokaryotic cyanobacteria/salt stress/halotolerant algae/molecular mechanisms of responses to salt stress引用本文复制引用
基金项目
国家重点研发计划政府间国际科技创新合作重点专项(2023YFE0108100)
出版年
2024
国家科技期刊平台
NSTL
万方数据