首页|Potential of adipose derived stem cell preparations in neurological repair and regeneration

Potential of adipose derived stem cell preparations in neurological repair and regeneration

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Stem cell therapy is a promising treatment for neurogenerative disease as well as inflammatory and immune mediated diseases.Decades of preclinical research has demonstrated stem cell ability to differ-entiate into multiple cell lineages and be utilised in regeneration and repair with their immunomodu-latory and immunosuppressive properties.This work has provided the fundamental scientific know-ledge needed to launch various clinical trials studying stem cell therapy in autoimmune disorders,stroke,and other tissue injury.Despite the early success many of these promising therapies are yet to breakthrough into clinical use.In this review,we highlight the recent developments in the use of stem cells as therapeutic agents for neurological conditions as well as their failures and how the clinical translation can be improved.

Adipose derived mesenchymal stem cellsMicro-fragmented adipose tissueSuicide gene therapy

Laura Combes、Xenia Sawkulycz、Wen-Hui Fang、Baoqiang Guo、Mark Slevin

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Department of Life Sciences,Manchester Metropolitan University,Manchester,UK

Department of Biological and Geographical Sciences University of Huddersfield,Huddersfield,UK

2021

生物物理学报
中国生物物理学会 中国科学院生物物理研究所

生物物理学报

影响因子:0.355
ISSN:1000-6737
年,卷(期):2021.7(2)
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