SCtool:A tool to identify genetic associations between complex traits and diseases
Identifying genetic associations between complex traits and diseases can provide useful etiological perspectives and help priorities possible causal relationships.Although many tools are available to implement genetic associations between complex traits and diseases,some tools have poor code readability,are based on different computer languages,and have poor inter-tool concatenation.Therefore,this study proposed SCtool,an open source,cross-platform and user-friendly software tool based on genome-wide association study(GWAS)data.The main function is to identify genetic correlations between complex traits and diseases and to explore potential causal associations between complex traits,between diseases,or between disease,based on GWAS summary level data.Finally,SCtool was used to reveal the genetic association between systemic iron status(Ferritin,Serum iron,Transferrin,Transferrin saturation)and epigenetic clock GrimAge.
国家科技期刊平台
NSTL
万方数据
