生物医学工程学杂志2024,Vol.41Issue(1) :41-50.DOI:10.7507/1001-5515.202304037

基于第二心音统计特征的先天性心脏病相关肺动脉高压诊断方法

Diagnosis of pulmonary hypertension associated with congenital heart disease based on statistical features of the second heart sound

杨炫锴 孙静 杨宏波 郭涛 潘家华 王威廉
生物医学工程学杂志2024,Vol.41Issue(1) :41-50.DOI:10.7507/1001-5515.202304037

基于第二心音统计特征的先天性心脏病相关肺动脉高压诊断方法

Diagnosis of pulmonary hypertension associated with congenital heart disease based on statistical features of the second heart sound

杨炫锴 1孙静 1杨宏波 2郭涛 2潘家华 2王威廉1
扫码查看

作者信息

  • 1. 云南大学信息学院(昆明 650504)
  • 2. 昆明医科大学附属心血管病医院(昆明 650102);云南省阜外心血管病医院(昆明 650102)
  • 折叠

摘要

针对先天性心脏病相关肺动脉高压听诊特征不明显,已有的机器辅助诊断算法相对复杂等问题,提出一种基于第二心音信号高频分量统计特征的分析方法.首先,采用端点检测自适应分割方法提取第二心音.其次,使用离散小波变换分解出高频分量,并提取该分量的赫斯特(Hurst)指数、勒佩尔-齐夫(Lempel-Ziv)信息和样本熵等统计特征.最后,使用这些特征训练极端梯度提升算法(XGBoost)分类器,在三分类中准确率达到了 80.45%.该方法无需进行降噪处理,特征提取速度快,且只需三个特征即可实现较好的多分类效果,有望用于先天性心脏病相关肺动脉高压早期筛查.

Abstract

Aiming at the problems of obscure clinical auscultation features of pulmonary hypertension associated with congenital heart disease and the complexity of existing machine-aided diagnostic algorithms,an algorithm based on the statistical characteristics of the high-frequency components of the second heart sound signal is proposed.Firstly,an endpoint detection adaptive segmentation method is employed to extract the second heart sounds.Subsequently,the high-frequency component of the heart sound is decomposed using the discrete wavelet transform.Statistical features including the Hurst exponent,Lempel-Ziv information and sample entropy are extracted from this component.Finally,the extracted features are utilized to train an extreme gradient boosting algorithm(XGBoost)classifier,which achieves an accuracy of 80.45%in triple classification.Notably,this method eliminates the need for a noise reduction algorithm,allows for swift feature extraction,and achieves effective multi-classification using only three features.It is promising for early screening of pulmonary hypertension associated with congenital heart disease.

关键词

心音/先天性心脏病/肺动脉高压/高频分量/统计特征/极端梯度提升算法

Key words

Heart sound/Congenital heart disease/Pulmonary arterial hypertension/High-frequency components/Statistical features/Extreme gradient boosting algorithm

引用本文复制引用

基金项目

国家自然科学基金资助项目(81960067)

2018云南省重大科技专项资助项目(2018ZF017)

出版年

2024
生物医学工程学杂志
四川大学华西医院 四川省生物医学工程学会

生物医学工程学杂志

CSTPCD北大核心
影响因子:0.432
ISSN:1001-5515
参考文献量24
段落导航相关论文