生物医学工程学杂志2024,Vol.41Issue(1) :144-151.DOI:10.7507/1001-5515.202305001

纤维的体积与材料特性以及髓核横截面积对椎间盘力学行为的影响研究

Effect of fiber volume and material property and nucleus pulposus area on intervertebral disc mechanical behavior

董瑞春 刘忠 郭云强 安钰坤 石舟 时明
生物医学工程学杂志2024,Vol.41Issue(1) :144-151.DOI:10.7507/1001-5515.202305001

纤维的体积与材料特性以及髓核横截面积对椎间盘力学行为的影响研究

Effect of fiber volume and material property and nucleus pulposus area on intervertebral disc mechanical behavior

董瑞春 1刘忠 2郭云强 1安钰坤 1石舟 1时明2
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作者信息

  • 1. 山东理工大学机械工程学院(山东淄博 255000)
  • 2. 淄博市中心医院脊柱外科与肿瘤科(山东淄博 255000)
  • 折叠

摘要

在不同研究中纤维的材料特性、体积比例以及髓核的横截面积比例差异很大,而这些因素对椎间盘力学行为的影响尚不明确.通过建立不同参数的椎间盘有限元模型研究椎间盘在压力、压力与角位移或压力与扭矩等载荷下的压力、高度变化、转动角度、应力和应变.结果发现,纤维材料特性对椎间盘力学行为有很大影响,特别是对转动角度的影响尤为显著.当纤维体积比例较小时,其变化对椎间盘的旋转角影响很大.髓核的面积比例对椎间盘力学行为的影响相对较小.在合理范围内通过适当调整纤维的弹性模量或体积比例,可以得到能够模拟正常椎间盘力学行为的模型.在椎间盘有限元模型中髓核的面积比例在25%~50%内是合理的.本文为椎间盘有限元模型创建和椎间盘退化机制研究提供了指导和参考.

Abstract

The material properties and volume proportion of the fibers as well as the cross-sectional area proportion of nucleus pulposus vary greatly in different studies.The effect of these factors on the mechanical behavior of intervertebral discs(IVDs)are uncertain.The IVDs finite element models with different parameters were created to investigate the pressure,height,rotation,stress,and strain of the IVDs under loads:pure compression,rotation after compression or axial moment after compression.The results showed that the material properties of fibers had great impact on the mechanical behavior of IVDs,especially on the rotation angle.When the fiber volume ratio was small,its changes had a significant impact on the rotation angle of the IVDs.The area proportions of nucleus pulposus had relatively little effect on the mechanical behavior of IVDs.The IVDs rotation should be observed when validating the model.By adjusting the elastic modulus or volume ratio of fibers within a reasonable range,a model that could simulate the mechanical behavior of normal IVDs could be obtained.It was reasonable to make the area proportion of nucleus pulposus within 25%-50%for the IVDs finite element model.This study provides guidance and reference for finite element modeling of the IVDs and the investigation of the IVDs degeneration mechanism.

关键词

椎间盘/力学行为/纤维体积/髓核面积

Key words

Intervertebral disc/Mechanical behavior/Fiber volume/Nucleus pulposus area

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基金项目

国家自然科学基金(52005305)

国家自然科学基金(51904179)

山东省自然科学基金(ZR2019BEE071)

中国博士后科学基金(2019M652443)

出版年

2024
生物医学工程学杂志
四川大学华西医院 四川省生物医学工程学会

生物医学工程学杂志

CSTPCD北大核心
影响因子:0.432
ISSN:1001-5515
参考文献量35
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