首页|自动胰岛素输送系统在糖尿病管理领域的研究进展

自动胰岛素输送系统在糖尿病管理领域的研究进展

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糖尿病及其并发症对人类生命健康构成了严重威胁,已成为全球广泛关注的公共卫生问题.目前,临床上主要采用注射胰岛素进行治疗,然而手动注射胰岛素的方式还存在诸多不足之处.近年来,随着研究的深入,发现结合连续血糖监测装置与胰岛素泵的自动胰岛素输送(AID)系统,能够显著改善糖尿病治疗效果并且降低患者并发症的发生率.本文首先介绍了 AID系统的组成及其工作原理,然后从连续血糖监测技术、胰岛素泵以及闭环控制算法的发展等方面,详细介绍了相关技术的发展历程及现状.最后,本文展望了 AID系统在糖尿病治疗领域的应用前景及未来发展方向,为进一步的研究提供理论参考.
Research progress on automated insulin delivery system in the field of diabetes management
Diabetes and its complications pose a serious threat to human life and health.It has become a public health problem of wide concern worldwide.Currently,diabetes is mainly treated with insulin injection in clinic.However,manual insulin injection still has many shortcomings.In recent years,with the deepening of research,it has been found that an automated insulin delivery system(AID),which combines a continuous glucose monitoring device with an insulin pump,can significantly improve the effectiveness of diabetes treatment and reduce the incidence of complications in patients.This paper firstly introduces the composition of the AID system and its working principle,and then details the development history and current status of the related technologies from the aspects of continuous glucose monitoring technology,insulin pumps and the development of closed-loop control algorithms,etc.Finally,this paper looks forward to the application prospect and future development of AID system in the field of diabetes treatment,providing theoretical reference for further research.

Automated insulin deliveryDiabetes mellitusInsulin pumpContinuous glucose monitoring

俞志超、孙宇帆、黄志健、李崭虹、龙建军、朱志刚

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上海理工大学健康科学与工程学院(上海 200093)

江苏鱼跃凯立特生物科技有限公司(江苏丹阳 212300)

自动胰岛素输送 糖尿病 胰岛素泵 连续血糖监测

2024

生物医学工程学杂志
四川大学华西医院 四川省生物医学工程学会

生物医学工程学杂志

CSTPCD北大核心
影响因子:0.432
ISSN:1001-5515
年,卷(期):2024.41(6)