Effect of ultrafiltration and sodium profile combination on hypotension in hemodialysis
Objective To investigate the effect of ultrafiltration and sodium profile combination on hypotension in hemodialysis. Methods A total of 20 patients with maintenance on hemodialysis and prone to hypotension were enrolled, male 9, female 11, aged 25 - 68 years old, mean age 44 years old, body weight was 46.0 - 72.5 kg, mean body weight was 59.9 kg. All of them were randomly divided into experimental group (n = 10, male 4, female 6) and control group(n = 10, male 5, female 5). The experimental group was performed ultrafiltration profile in combined with sodium profile dialysis while the control group was performed standard mode dialysis for 1 month (12 times). Serum sodium concentration, blood pressure and hypotension incidence were compared before and after dialysis between 2 groups. Results The ultrafiltration volume and body weight had not significant difference between 2 groups (P > 0.05); Blood pressure before dialysis and changed in the first half of dialysis period were not significant difference between 2 groups(P> 0.05), the difference of blood pressure in the second half had statistically significant change between 2 groups(P < 0.05). In dialysis, the incidence of hypotension was 17 % in experimental group, and 41 % in control group, the difference had statistically significant(P < 0.01). The serum sodium concentration after 4-hour dialysis had not significant difference between 2 groups(P > 0.05). Conclusion It is demonstrated that the ultrafiltration and sodium profile combination could effectively prevent the occurrence of dialysis-related hypotension, and have no significant effect on the concentration of serum sodium as well.
NETL
NSTL
万方数据
维普
