首页|超声测定Tei指数和LVEDV、LVESV、SV评估足月小样儿心功能变化的研究

超声测定Tei指数和LVEDV、LVESV、SV评估足月小样儿心功能变化的研究

Evaluation of cardiac function change in full-term small-for-date infant on Tei index,LVEDV,LVESV and SV measured by ultrasound

扫码查看
目的 探究超声测定心肌做功指数(Tei指数)和左心室舒张末期容积(LVEDV)、左心室收缩末期容积(LVESV)、每搏量(SV)对足月小样儿心功能变化评估价值.方法 选择2020年11月至2022年11月在邢台市中心医院出生的100例足月小样儿(研究组),其中男性47例,女性53例;胎龄37~41+6周,平均胎龄39.62周;体质量2.07~2.43 kg,平均体质量2.12 kg.依据足月小样儿胎龄将新生儿分为早期足月小样儿(37~38+6周)组,晚期足月小样儿(39~41+6周)组,每组50例.另选择医院同期出生的50例健康足月新生儿(对照组),其中男性25例,女性25例;胎龄38~40+6周,平均胎龄39.33周;体质量2.53~4.00 kg,平均体质量3.07 kg.采用超声测定3组Tei指数和LVEDV、LVESV、SV、左心室射血分数(LVEF)、心输出量(CO),左右心大血管内径、室壁厚度、心内径指标,二、三尖瓣心舒张功能指标,进而评估足月小样儿心功能变化情况.结果 对照组、早期足月小样儿组、晚期足月小样儿组左右心室等容收缩期时间(ICT)+等容舒张期时间(IRT)、射血期时间(ET)依次降低,Tei指数依次升高,差异有统计学意义(P<0.05).对照组、早期足月小样儿组、晚期足月小样儿组 SV[(3.50±0.94)mL vs(2.96±0.63)mL vs(2.55±0.48)mL]、LVEDV[(5.07±1.19)mL vs(4.71±1.05)mL vs(4.49±0.93)mL]、LVEF[(71.53±4.52)%vs(66.19±3.21)%vs(63.44±2.98)%]、CO 指数[(0.75±0.09)Umin vs(0.51±0.13)Umin vs(0.44±0.17)Umin]依次降低,LVESV 指数依次升高[(1.46±0.37)mL vs(1.59±0.41)mL vs(1.66±0.43)mL],差异有统计学意义(P<0.05).对照组、早期足月小样儿组、晚期足月小样儿组主动脉根部内径(AOD)[(6.9±1.0)mm vs(6.0±0.8)mm vs(5.5±0.5)mm]、左心室后壁舒张末期厚度(LVPWD)、左心房收缩期末期内径(LAD)、左心室收缩末期内径(LVDS)、左心室舒张末期内径(LVDD)指数依次降低,差异有统计学意义(F=39.947、37.000、27.820、34.742、27.990,P<0.05).对照组、早期足月小样儿组、晚期足月小样儿组室间隔舒张末期厚度(IVSD)、平均动脉压(MAP)、右心室前壁厚度(RVAW)、右心室舒张末期内径(RVDD),差异有统计学意义(F=16.107、11.868、39.000、9.511,P<0.05).对照组、早期足月小样儿组、晚期足月小样儿组A、E/A值依次升高,组间比较,差异有统计学意义(F=7.401、35.399,P<0.05).结论 足月小样儿的超声测定Tei指数和LVEDV、LVESV、SV、CO较健康足月新生儿改变明显,在心功能变化评估中具有重要意义.
Objective To explore the evaluation value of Tei index,left ventricular end diastolic volume(LVEDV),left ventric-ular end systolic volume(LVESV),stroke volume(SV)and myocardial performance index(MPI)measured by ultrasound on car-diac function change in full-term small-for-date infant.Methods From November 2020 to November 2022,a total of 100 full-term infants were enrolled as study group,which included 47 males and 53 females;gestational age was 37-41+6 weeks with mean gestational age of 39.62 weeks;body mass was 2.07-2.43 kg with mean body mass of 2.12 kg.According to gesta tional age,the infants were divided into early full-term small-for-date infant group(37-38+6 weeks)and late full-term small-for-date infant group(39-41+6 weeks),with 50 cases in each group.Fifty healthy full-term newborns from the same period were enrolled as control group,which included 25 males and 25 females;gestational aged 38-40+6 weeks with mean gesta-tional age of 39.33 weeks;body mass was 2.53-4.00 kg with mean body mass of 3.07 kg.Tei index,LVEDV,LVESV,SV,left ventricular ejection fraction(LVEF),cardiac output(CO),left and right cardiac vascular diameter,wall thickness,cardiac diameter index,mitral and tricuspid diastolic function index were measured by ultrasound,and cardiac function changes in full-term small-for-date infant were evaluated.Results The isovolumic contraction time(ICT)+isovolumic relaxation time(IRT)and ejection time(ET)of the left and right ventricles in control group,early full-term small-for-date infant group and late full-term small-for-date infant group were sequentially decreased,while Tei indexes of 3 groups sequentially increased,and the differences were statistically significant(P<0.05).The control group,early full-term small-for-date infant group and late full-term small-for-date infant group were observed sequentially decreased in SV[(3.50±0.94)mL vs(2.96±0.63)mL vs(2.55±0.48)mL],LVEDV[(5.07±1.19)mLvs(4.71±1.05)mL vs(4.49±0.93)mL],LVEF[(71.53±4.52)%vs(66.19±3.21)%vs(63.44±2.98)%],CO index[(0.75±0.09)L/min vs(0.51±0.13)Umin vs(0.44±0.17)Umin],and sequentially increased in LVESV index[(1.46±0.37)mLvs(1.59±0.41)mL vs(1.66±0.43)mL],and the differences were statistically significant(P<0.05).The control group,early full-term small-for-date infant group and late full-term small-for-date infant group were observed sequentially decreased in aortic root diameter(AOD)[(6.9±1.0)mm vs(6.0±0.8)mm vs(5.5±0.5)mm],left ventricular posterior wall end-diastolic thickness(LVPWD),left atrial end-systolic diameter(LAD),left ventricular end-systolic diameter(LVDS)and left ventricular end-diastolic diameter(LVDD),and the differences were statistically significant(F=39.947,37.000,27.820,34.742,27.990,P<0.05).There were significant differences on thickness of interventricular septal end-diastolic(IVSD),mean arterial pressure(MAP),thickness of right ventricular anterior wall(RVAW)and right ventricular end-diastolic diameter(RVDD)in control group,early full-term small-for-date infant group and late full-term small-for-date infant group(F=16.107,11.868,39.000,9.511.P<0.05).The A and E/A value of control group,early full-term small-for-date infant group and late full-term small-for-date infant group were sequentially increased,and the differences in groups were statistically significant(F=7.401,35.399,P<0.05).Conclusion It is demonstrated that Tei index,LVEDV,LVESV,SV,CO measured by ultrasound in full-term small-for-date infant are significantly different from those of healthy full-term newborns,which is of great significance in evaluat-ing cardiac function changes.

ultrasoundTei indexleft ventricular end diastolic volume(LVEDV)left ventricular end systolic volume(LVESV)stroke volume(SV)full-term sample

靳雅玲、王亚东、李洁、何颖、范雪爱

展开 >

邢台市中心医院儿童保健科,河北 邢台 054099

邢台市中心医院新生儿科,河北 邢台 054099

超声 Tei指数 左心室舒张末期容积(LVEDV) 左心室收缩末期容积(LVESV) 心搏量(SV) 足月小样儿

邢台市科技局重点研发计划

2022zz082

2024

生物医学工程与临床
天津市生物医学工程学会,天津市第三中心医院

生物医学工程与临床

CSTPCD
影响因子:0.462
ISSN:1009-7090
年,卷(期):2024.28(3)