Accuracy analysis of conventional ultrasound and UE combined with DBT in differential diagnosis of benign and ma-lignant breast masses
Objective To evaluate the accuracy of conventional ultrasound and ultrasonic elastography(UE)combined with digital breast tomosynthesis(DBT)in differential diagnosis of benign and malignant breast masses.Methods From January 2022 to December 2023,a total of 152 patients with breast mass were enrolled,which aged 22-65 years old with mean age of 44.12 years old;body mass index(BMI)was 18-26 kg/m2 with mean BMI of 22.45 kg/m2.There were 100 cases of mass was located on the left side and 52 on the right side.The tumor diameter was 0.5-4.7 cm with mean diameter of 2.33 cm.All of them performed conventional ultrasound,UE and DBT.The qualitative diagnostic value of conventional ul-trasound,UE and DBT alone and in combination was compared with gold standard of surgical pathological diagnosis.The conventional ultrasound parameters,UE parameters and DBT parameters of patients with benign and malignant breast masses were compared.Results The surgical pathological diagnosis showed that 152 patients were all solitary nodules(among 152 masses,84 were malignant and 68 were benign).There was no significant difference in diagnostic efficacy of conventional ultrasound,UE and DBT single for benign and malignant breast masses(P＞0.05),the sensitivity of combined diagnosis was sta-tistically significantly higher than single diagnosis(95.24％vs 71.43％,76.19％,73.81％.P＜0.05).The elastic strain rate,mass diameter,diameter change rate,mass area,area ratio,and proportion of marginal sharpness in malignant patients were sig-nificantly lower(2.92％±0.54％vs 6.06％±1.72％,13.56 mm±3.32 mm vs 19.78 mm±3.72 mm,0.22％±0.05％vs 0.39％±0.12％,8.68 cm2±1.72 cm2 vs 16.54 cm2±3.18 cm2,1.21％±0.24％vs 1.92％±0.36％,4.76％vs 73.53％),and the UE score,blood flow signal grade,edge blurring,shielding,burr,mass structure distortion,increased blood supply,and vascular penetration were significantly higher than those in benign patients,and the difference between the groups was statisti-cally significant(P＜0.05).Conclusion It is demonstrated that combined application of conventional ultrasound,UE and DBT can accurately diagnose the benign and malignant breast masses,and the imaging signs can be used as the basis of evaluation,which have significant application value.
conventional ultrasoundultrasonic elastographydigital breast tomosynthesisbreast tumorbenign and malignant classificationultrasonic signs
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