首页|从"阴火论"探讨膜性肾病的治疗

从"阴火论"探讨膜性肾病的治疗

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膜性肾病是一种以蛋白尿、水肿为主要临床表现的肾小球疾病,为难治性肾病之一,其病因及发病机制尚未完全阐明.李东垣著《脾胃论》创立阴火学说,提出脾胃虚损为百病之源.通过梳理其阴火理论的渊源及治法研究,发现脾肾亏虚、阴火内动与膜性肾病的发生和发展密切相关,精微下泄、湿阻瘀滞、热郁毒蕴是膜性肾病的核心病机,发病过程中虚、湿、热、瘀四者之间相互影响,互为因果,终成虚实夹杂之证.秉承李东垣治疗阴火之法,根据膜性肾病临床特点,采用"安中健脾,固本培元;升阳泻火,祛湿化瘀"的治疗原则,对其辨证施治,可资临证参考.
Treatment of Membranous Nephropathy Based on"Yinhuo Theory"
Membranous nephropathy is a glomerular disease with proteinuria and edema as the main clinical manifestations,which is one of the refractory nephropathies.Its etiology and pathogenesis have not been fully elucidated.Li Dongyuan established Yinhuo theory in his Treatise on the Spleen and Stomach,and put forward that deficiency of spleen and stomach was the source of all diseases.By analyzing the origin and treatment research of Yinhuo theory,it was found that the spleen and kidney deficiency and interior Yinhuo were closely related to the occurrence and development of membranous nephropathy.The core pathogenesis of mem-branous nephropathy included nutrient leakage,dampness and stasis,and heat and poison accumulation.Deficiency,dampness,heat and blood stasis interact with each other in the course of the disease,and eventually form the syndrome of deficiency and excess mixed.This paper adopts Li Dongyuan's method of treating Yinhuo,according to the clinical characteristics of membranous nephrop-athy,the treatment principle of"invigorating the spleen,strengthening the essence,rising yang and purging fire,removing dampness and blood stasis"can be used as a reference for clinical practice.

membranous nephropathyYinhuodeficiency of spleen and kidneyLi DongyuanTreatise on the Spleen and Stomach

祝昌昊、王耀光

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天津中医药大学第一附属医院,天津 300381

国家中医针灸临床医学研究中心,天津 300381

膜性肾病 阴火 脾肾亏虚 李东垣 脾胃论

国家重点研发计划子课题国家中医药管理局建设项目(王耀光全国名老中医药专家传承工作室)天津市名中医传承工作室建设项目(王耀光天津市名中医传承工作室)

2018YFC1704102978022883022

2024

山西大同大学学报(自然科学版)
山西大同大学

山西大同大学学报(自然科学版)

影响因子:0.271
ISSN:1674-0874
年,卷(期):2024.40(1)
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