Advances in the Dynamic Behavior of Feedforward Loop and Feedback Loop
Networks are composed of a small set of recurring interaction patterns called motifs.Two of the most common motifs in the biological networks are feedforward loop(FFL)and feedback loop(FBL),which have been extensively studied,respectively.Al-though there are many instances that FFL and FBL co-exist in biological networks,there is still a lack of clear understanding on their dynamic behaviors.In this review,we first describe the structure and function of the FFL.Then,we summarize the structure and dy-namical behavior of FFL,focusing on the current status of research on two important dynamical behaviors,i.e.,multistability and os-cillation.Finally,we give some biological examples that contain both FFL and FBL,emphasizing the importance of studying the dy-namical behavior of such coupled networks.
国家科技期刊平台
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